Wednesday, August 22, 2012

Can an Antibiotic Fight Schizophrenia?

BEFORE I GET INTO The BLOG, I WOULD LIKE TO REMIND OUR READERS THAT The RECOVERY BLOG IS MOVING TO A NEW LOCATION: OUR BLOG WILL CONTINUE FROM OUR NEW HOME: That is what this article says that maybe it can lead to a new discovery for this type of antibiotic. “Five years ago, a Japanese psychiatrist and his colleagues observed something peculiar regarding two schizophrenia patients. One was a 23-year old man who had been hospitalized for a first episode of schizophrenia. While in the hospital he developed a severe case of pneumonia, which was treated with the antibiotic minocycline. Two weeks later, his schizophrenia symptoms resolved along with his pneumonia.” Is it only this type of antibiotic or is it all of them? This was this man’s first episode so I wonder if that has something to do with it also.
The article says there was a second person: “The other was a 61-year old man who was diagnosed with schizophrenia at age 20. During his most recent hospitalization for it, he developed a bedsore that was treated with minocycline. Two weeks later, the bedsore healed, and minocycline was discontinued. The patient’s schizophrenia symptoms worsened. Minocycline was resumed; within three days, the patient’s schizophrenia symptoms improved.” It has nothing to do with just the first time so this is pretty exciting news. Of course they will need more research. Although something made it work twice.
The article goes on to say: “I was surprised by these developments,’ the psychiatrist-Tsuyoshi Miyaoka, M.D., an associate professor of psychiatry at Japan’s Shimane University School of Medicine- told Psychiatric News. ‘Could minocycline have antipsychotic properties? I wondered.” It must be just this one antibiotic. I only take antibiotics when I get a sinus infection at least twice a year. I never feel different except I am sick. Maybe this one antibiotic does have antipsychotic properties.
In the article they go on to talk about how they gave this antibiotic to patients who had severe schizophrenia and it worked even one stayed out in the community. It even helps with negative symptoms and a lot of schizophrenia patients hate those negative symptoms they cannot get rid of. “So what about this antibiotic is leading to hope that it can be a weapon against schizophrenia, and especially the usually intractable negative symptoms and cognitive deficits of the illness? ‘We don’t really know for sure,’ Kelly acknowledged. ‘But minocycline is known to be capable of countering inflammation and of crossing the blood-barrier into the brain, and there is growing evidence that inflammation might play a role in the pathophysiology of schizophrenia. So minocycline might be able to counter schizophrenia by countering inflammation in the brain.” It is just this antibiotic. To help with negative symptoms would be an improvement in the fight of schizophrenia.
They are not stopping here there are more randomized trials going on to see if this really works. “Since all [experimental drugs for negative symptoms or cognitive deficits in schizophrenia] have failed to date, you’ve got to bet that the next one will fail as well… ‘But…if minocycline has efficacy for negative symptoms, cognitive impairment, or both, that would be terrific…and transformative for the field.” A person can only hope that it will bring relief to those that have negative symptoms. A last word from the doctor that found this antibiotic property: “From our experience and clinical research, I believe that minocycline will turn out to be a truly revolutionary treatment for schizophrenia,’ Miyaoka declared.” A lot of things are found out by accident we can only hope this is one of them.  Please do not try and get an infection.  Please wait till they find out if it works or not. JUST A REMINDER THAT THE RECOVERY BLOG IS MOVING TO A NEW ADDRESS: OUR NEW HOME IS:

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